Bioactive Lipids in Cancer, Inflammation and Related Diseases



Invited Speakers provide approximately 50% of the lectures with the remaining oral lectures chosen from submitted abstracts, including junior investigators. In addition, there will be approximately 125 scientific poster presentations selected by abstract submissions. 

Robert J. Lefkowitz, MD

Investigator, Howard Hughes Medical Institute

James B. Duke Professor of Medicine

Professor of Biochemistry and Chemistry

Duke University

Nobel Prize in Chemistry (2012) for studies

of G-protein-coupled receptors

G-Protein coupled receptors

Dr. Takao Shimizu, MD, PhD (see biography)

Professor, Department of Biochemistry Faculty of Medicine University of Tokyo Japan

Challenge for lipid diversity; from bioactive mediators to membrane biology


Nicolas G. Bazan, MD, PhD

Boyd Professor

Ernest C. and Yvette C. Villere

Chair for Retinal Degenerations

Professor of Biochemistry and Molecular Biology;

Ophthalmology and Neurology;

Director, Neuroscience Center of Excellence

Louisiana State University Health Sciences Center

New Orleans, LA

Foreign Adjunct Professor of Neuroscience

Karolinska Institutet – Stockholm, Sweden

Uncovering rules to sustain neurons’ long lives: signaling redundancy and resiliency at the onset of Alzheimer’s disease

Haydee E.P. Bazan, PhD, FARVO

Professor, Ophthalmology

Biochemistry and Molecular Biology and Neuroscience

Louisiana State University Health Science Center

Novel RvD6 isomer promotes cornea nerve regeneration displaying a trigeminal transcriptome signature

Michael Holinstat, PhD, FAHA

Associate Professor of Pharmacology

Internal Medicine and Vascular Surgery

Director, Platelet Pharmacology and Physiology Core

University of Michigan

Untapped potential: Using eicosanoids to identify therapeutic targets in the blood

Nancy J. Brown, MD

Jean and David W. Wallace Dean of Medicine

C.N.H. Long Professor of Internal Medicine

Yale School of Medicine

Metabolic effects of genetic and pharmacologic variation in soluble epoxide hydrolase

Jerold Chun, MD, PhD

Professor, Degenerative Diseases Program

Senior Vice President, Neuroscience Drug Discovery

Center for Genetic Disorders and Aging Research

A quarter-century of lysophospholipid receptors: one view from the brain

Jason G. Cyster, PhD

Professor, Microbiology and Immunology

Investigator of the Howard Hughes Medical Institute

University of California, San Francisco

S-geranylgeranyl-l-glutathione as immune cell guidance factor

Catherine Godson, PhD

Member of the Royal Irish Academy Professor

Diabetes Complications Research Centre

Conway Institute & School of Medicine

University College Dublin

Synthetic lipoxin mimetics attenuate inflammation and suppress fibrosis

Barbara Kahn, MD

Vice Chair of Research Strategy

Department of Medicine, Division of Endocrinology,

Diabetes, and Metabolism

George R. Minot Professor of Medicine

Harvard Medical School

New biology of bioactive branched fatty acid esters of hydroxy fatty acids

Jesper Z. Haeggström, MD, PhD

Professor, Medical Biochemistry and Biophysics Division of

Physiological Chemistry Karolinska Institutet

The leukotriene Pathway, from crystal structures to novel therapeutics

Makoto Murakami, PhD

Professor, Graduate School of Medicine

Laboratory of Microenvironmental and Metabolic Health Science

Center for Disease Biology and Integrative Medicine

University of Tokyo

The phospholipase A2 superfamily as a central hub of bioactive lipids and beyond

Junken Aoki, PhD

Professor, Graduate School of Pharmaceutical Sciences Tohoku University, Japan

Lysophospholipid mediators positively and negatively regulate immune responses

Myriam Baes, PhD

Professor, Pharmaceutical and Pharmacological Sciences Lab of Cell Metabolism KU Leuven Leuven, Belgium

Peroxisomal b-oxidation is crucial for retinal integrity by controlling DHA and VLC-PUFA homeostasis

Magnus Bäck, MD, PhD

Professor, Cardiology Karolinska Institutet Stockholm, Sweden

Lipid mediator receptors transducing the resolution of inflammation in cardiovascular disease

Richard P. Bazinet, PhD

Professor and Canada Research Chair in Brain Lipid Metabolism University of Toronto

Novel methods using natural abundance carbon isotope ratios to study the turnover and metabolism of fatty acids reveals how docosahexaenoic acid regulates its own synthesis

Laura M. Bohn, PhD

Professor, Molecular Medicine & Neuroscience The Scripps Research Institute Jupiter, Florida

Noncompetitive agonists as a means of MOR activation and antinociception

Eric Boilard, PhD

Professor, Microbiology and Immunology Researcher, CHU de Quebec Research Center Laval University School of Medicine

Role of secreted phospholipase A2-IIA bactericidal activity in sterile inflammation

Jorgelina M Calandria, PhD

Research Assistant Professor, Neurology and Neuroscience Louisiana State University Health Science Center

Elovanoids and other lipid mediators elicit protective actions in Parkinson’s model

Chu Chen, PhD

Professor, Cellular and Integrative Physiology Joe R. and Teresa Lozano Long School of Medicine UT Health Science Center at San Antonio

Endocannabinoid metabolism in neurodegenerative diseases

Nan Chiang, PhD

Assistant Professor and Principal Associate Brigham and Women’s Hospital Department of Anesthesiology Perioperative and Pain Medicine Harvard Medical School

Resolvins, human neutrophil traps, COVID-19 and coagulopathies

Jesmond Dalli, PhD

Professor, Molecular Pharmacology The William Harvey Research Institute Barts and The London Queen Mary University of London

Promoting tissue repair by reprogramming immune cells

Yusuke Endo PhD

Head, Laboratory of Medical Omics Research Kazusa DNA Research Institute

Lipid metabolism in Th17 cell function

Megan L. Falsetta, PhD

Assistant Professor, Obstetrics and Gynecology and Pharmacology and Physiology University of Rochester Medical Center

Dysregulation of pro-resolving lipids predisposes women to chronic vulvar pain and illuminates new therapeutic targets

Gabrielle Fredman, PhD

Associate Professor, Molecular and Cellular Physiology Albany Medical College

Specialized pro-resolving mediators limit senescent cells in atherosclerotic plaques

Scott Hansen, PhD

Associate Professor, Molecular Medicine Associate Professor, Neuroscience The Scripps Research Institute

Regulation of neuroinflammation by astrocyte-derived cholesterol.

Miriam Kolko, MD, PhD

Professor, Translational Eye Research Department of Ophthalmology University of Copenhagen Chief Physician, Copenhagen University Hospital

Is fat the future for saving sight? Bioactive lipids and their impact on glaucoma

Gerard Lambeau, IPMC, CNRS

Institute of Pharmacology Universite Cote d’Azur Nice-Sophia Antipolis, France

Novel functions of sPLA2s, role of inhibitors and PLA2R1

Bodo Levkau, MD

Professor and Chair Institute for Molecular Medicine III University Hospital and Heinrich Heine University Düsseldorf

Sphingosine-1-phosphate suppresses GLUT activity and counteracts hyperglycemia in red blood cells

Bruce D. Levy, MD

Parker B. Francis Professor of Medicine Harvard Medical School Chief, Division of Pulmonary and Critical Care Medicine Brigham and Women’s Hospital

Phospholipid phosphatase 6 is an intracellular target for SPMs and regulates dendritic cell cholesterol, macropinocytosis and allergen sensitization

Krishna Rao Maddipati, PhD

Professor, Department of Pathology Director – Lipidomics Core Facility Wayne State University

“Inflammation” in homeostasis is more than just good inflammation

Liza Makowski, PhD

Professor, Dept. of Medicine – Division of Hematology and Oncology Department of Microbiology, Immunology, and Biochemistry Department of Pharmaceutical Sciences University of Tennessee Health Science Center

Response to immune checkpoint blockade was improved in pre-clinical model of breast cancer after bariatric surgery

Gennaro (Gerry) Melino, MD, PhD

Professor and Director, Molecular Biology University of Rome – Tor Vergata Head, Apoptosis & Cancer Laboratory Medical Research Council Toxicology Unit, United Kingdom

The expression of ELOVL4, repressed by MYCN, defines neuroblastoma patients with good outcome

Anna Nicolaou, PhD

Professor of Biological Chemistry Faculty of Biology Medicine and Health University of Manchester, UK

Bioactive lipids mediating the cutaneous response to ageing: the impact of menopause on epidermal ceramides

Dipak Panigrahy, MD

Assistant Professor of Pathology Beth Israel Deaconess Medical Center Harvard Medical School

Cancer progression: Failure of resolution of inflammation

Marianne Schultzberg

Professor, Neurobiology, Care Sciences & Society Karolinska Institutet

Bioactive lipid mediators in Alzheimer’s disease

Patricia J. Sime, MD

Chair, Department of Internal Medicine William Branch Porter Professor of Medicine Virginia Commonwealth University School of Medicine

Exacerbations of chronic lung disease and disrupted resolution

Sarah Spiegel, PhD

Professor and Chair Department of Biochemistry and Molecular Biology Mann T. and Sara D. Lowry Chair of Oncology Virginia Commonwealth University School of Medicine

Bioactive sphingolipid metabolites regulate ER contacts with late endocytic organelles and cholesterol trafficking

Yukihiko Sugimoto, PhD

Professor, Pharmaceutical Biochemistry Graduate School of Pharmaceutical Sciences Faculty of Life Sciences Kumamoto University

Prostaglandin EP4 axis promotes lipolysis and fibrosis in adipose tissue

Thomas E. Van Dyke, DDS, PhD

Vice President and Senior Member of Staff Forsyth Institute Professor or Oral Medicine, Infection and Immunity Faculty of Medicine, Harvard University

Inflammation and stem cell activity in periodontal regeneration

Valeria Vásquez, PhD

Associate Professor, Physiology The University of Tennessee Health Science Center

Dietary fatty acids to alleviate neuropathic pain

Darryl C. Zeldin, MD

Scientific Director NIH/NIEHS Senior Investigator, Immunity Inflammation and Disease Laboratory Environmental Cardiopulmonary Disease Group

Genetic disruption of Cyp2c genes in mice does not affect EET levels in vivo but alters bile acid homeostasis leading to cholestatic liver disease

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